Is the 2,3-carbon-carbon bond of indole really inert to oxidative cleavage by Oxone?--synthesis of isatoic anhydrides from indoles.
نویسندگان
چکیده
A recent report has indicated that the oxidizing agent Oxone does not possess the ability to cleave the 2,3-carbon-carbon bond of indole. Work in our laboratory shows that this is not the case. Indole and a variety of aryl ring substituted derivatives readily react to form synthetically important isatoic anhydrides.
منابع مشابه
Sulfonated Porous Carbon (SPC): An efficient and recyclable solid acid catalyst for one-pot three-component synthesis of 2,3-dihydroquinazolin-4(1H)-ones under solvent-free conditions
A simple and efficient procedure has been developed for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones derivatives under solvent-free conditions. This method uses the condensation of isatoic anhydride, aldehydes, and amines in the presence of a catalytic amount Sulfonated Porous Carbon (SPC). One of the important advantages of the new method is that the SPC could be recycled and reused.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 11 43 شماره
صفحات -
تاریخ انتشار 2013